COVID-19 Vaccine Appointment Registration Information for ALL ELIGIBLE GROUPS!


If you are unable to click on the link for a certain clinic date that means the clinic is full for that day or even that week. 

January 21, 2021

Starting, Thursday, January 21, 2021, The Polk County Health Department and select Hy-Vee and Medicap pharmacies will open COVID-19 vaccine appointments to 65 years and older pending vaccine allocation at their pharmacy locations. Partners will continue to vaccinate Phase 1A during this time.

February 1, 2021, COVID-19 vaccine appointments will be open to:

  • 65 years and older
  • First Responders
  • PK-12 staff, early childhood education, childcare workers
  • 1A: Healthcare workers and long term care facilities staff and residents

COVID-19 vaccine appointments will be available based on vaccine availability. To

Please note appointment availability is based on the supply of vaccine for the week. 

Healthcare workers eligible for vaccination must meet the following criteria:

  • Healthcare personnel (HCP) with direct patient contact and thus who are unable to telework, including those who work in inpatient, outpatient, or community settings, who provide services to patients or patient's family members, or who handle infectious materials
  • Health care personnel are defined as paid and unpaid persons serving in health care settings who have the potential for direct or indirect exposure to patients or infectious materials.


Healthcare workers who now may be vaccinated in Phase 1A include:

Employees of Unaffiliated Medical Practices

Occupational Health staff

Respiratory Therapists

Emergency Medical Services

Pharmacists providing vaccinations

Healthcare Students (in clinical rotations or providing direct patient care)

School Nurses

Dentists and dental professionals

Clinical laboratory Staff        

Hospice Staff

Physical Therapists

Rehabilitation staff    

Environmental Services staff

Blood Bank Staff

Dialysis Center Staff

Mental Health Professionals providing IN-PERSON services


Home health Staff     


funeral home directors and staff


Vaccine Locations

Vaccine is available at the several locations in Polk County.  ALL locations will require that healthcare workers bring the following to their appointment:

  • Mask: everyone will be required to wear one. If you do not have one, a mask will be provided to you.
  • Photo form of personal identification: driver’s license, passport, or state identification card AND employment verification: employer issued badge or identification or proof of licensure.
  • If you are pregnant or lactating, you are required to consult with your Primary Care Physician before-hand and come with a note from them stating you are ok to receive the vaccine.

Polk County Health Department

1907 Carpenter Avenue

Des Moines, IA 50314



Hy-Vee Pharmacies and Drake University

Hy-Vee Pharmacy 

4605 Fleur Drive

Des Moines, IA 50321


Hy-Vee Pharmacy

108 8th Street SW

Altoona, IA 50009


Hy-Vee Pharmacy 

2510 S.W. State Street

Ankeny, IA 50023


Hy-Vee Pharmacy

555 South 51st Street

West Des Moines, IA 50265


Hy-Vee Pharmacy 

410 N. Ankeny Blvd

Ankeny, IA 50021

Hy-Vee Pharmacy

1107 SE Army Post Road   
Des Moines, IA 50315

Hy-Vee Pharmacy 

4815 Maple Drive

Pleasant Hill, IA 50327


Hy-Vee Pharmacy

8701 Douglas Avenue  

Urbandale, IA 50322


Hy-Vee Pharmacy      

1990 Grand Avenue     

West Des Moines, IA 50265


Drake University Harkin Center

2800 University Avenue

Des Moines, IA 50311

Please enter from 29th Street

Hy-Vee Pharmacy

3221 SE 14th Street Des Moines, Iowa 50320


Hy-Vee Pharmacy

3300 Martin Luther King Parkway, Des Moines, Iowa, 50310  515-255-6231



Medicap Pharmacies


Medicap Pharmacy

250 SE Gateway Drive

Grimes, IA 50111


Medicap Pharmacy

2527 Easton Blvd.

Des Moines, IA 50317


Medicap Pharmacy

8170 Douglas Avenue

Urbandale, IA 50322


Medicap Pharmacy

107 NE Delaware Ave # 6

Ankeny, IA 50021


Medicap Pharmacy

950 28th Ave SW

Altoona, IA 50009


Medicap Pharmacy

1300 East 14th St.

Des Moines, Iowa, 50316  


Medicap Pharmacy

2804 Beaver Ave.  Des Moines, Iowa 50310






If there are no appointments available, please check back periodically.  Additional appointments will be added as vaccine becomes available.

If you have questions regarding a specific location, please contact the pharmacy directly at the phone number listed for that site.


If you think you need to get tested for COVID-19 or have been exposed, call your clinic FIRST. DO NOT go to the ER or clinic. You could potentially expose others to COVID-19 or be exposed to COVID-19.